Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000504.4

p.M336V

c.1006A>G

Surrounding Variants

1 paper

NM_000504.4

p.M336T

c.1007T>C

2 papers

NM_000504.4

p.V338M

c.1012G>A

2 papers

NM_000504.4

p.A339T

c.1015G>A

1 paper

NM_000504.4

p.C342Y

c.1025G>A

1 paper

NM_000504.4

p.P344S

c.1030C>T

5 papers

NM_000504.4

p.R327W

c.979C>T

1 paper

NM_000504.4

p.R346C

c.1036C>T

1 paper

NM_000504.4

p.I323M

c.969C>G

2 papers

NM_000504.4

p.W348L

c.1043G>T

4 papers

NM_000504.4

p.D322N

c.964G>A

2 papers

NM_000504.4

p.E350K

c.1048G>A

1 paper

NM_000504.4

p.F321L

c.963C>A