Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000504.4

p.T358T

c.1074G>A

Surrounding Variants

5 papers

NM_000504.4

p.T358M

c.1073C>T

1 paper

NM_000504.4

p.G359insFs

c.1075_1076ins5

1 paper

NM_000504.4

p.G359fs

c.1075_1076fs

1 paper

NM_000504.4

p.G359W

c.1075G>T

2 papers

NM_000504.4

p.Q356*

c.1066C>T

1 paper

NM_000504.4

p.Q356delFs

c.1067delA

1 paper

NM_000504.4

p.T355M

c.1064C>T

3 papers

NM_000504.4

p.S362N

c.1085G>A

6 papers

NM_000504.4

p.G363S

c.1087G>A

2 papers

NM_000504.4

p.M354R

c.1061T>G

1 paper

NM_000504.4

p.L353P

c.1058T>C

1 paper

NM_000504.4

p.F364L

c.1090T>C