Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000504.4

p.F364L

c.1090T>C

Surrounding Variants

1 paper

NM_000504.4

p.F364L

c.1092C>A

1 paper

NM_000504.4

p.F364L

c.1092C>G

6 papers

NM_000504.4

p.G363S

c.1087G>A

3 papers

NM_000504.4

p.S362N

c.1085G>A

7 papers

NM_000504.4

p.R366C

c.1096C>T

6 papers

NM_000504.4

p.R366H

c.1097G>A

1 paper

NM_000504.4

p.T367T

c.1101C>G

1 paper

NM_000504.4

p.H368Q

c.1104C>A

1 paper

NM_000504.4

p.H368Q

c.1104C>G

1 paper

NM_000504.4

p.G359insFs

c.1075_1076ins5

1 paper

NM_000504.4

p.G359fs

c.1075_1076fs

1 paper

NM_000504.4

p.G359W

c.1075G>T