Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000504.4

p.V382A

c.1145T>C

Surrounding Variants

5 papers

NM_000504.4

p.P383S

c.1147C>T

1 paper

NM_000504.4

p.Y384_S389delFs

c.1151_1167del17

2 papers

NM_000504.4

p.Y384C

c.1151A>G

1 paper

NM_000504.4

p.E381delFs

c.1141delG

1 paper

NM_000504.4

p.Y384*

c.1152C>A

1 paper

NM_000504.4

p.Y384*

c.1152C>G

1 paper

NM_000504.4

p.V385M

c.1153G>A

1 paper

NM_000504.4

p.L380del1

c.1138_1139delCTG

5 papers

NM_000504.4

p.R387C

c.1159C>T

1 paper

NM_000504.4

p.R387insFs

c.1160_1161insT

5 papers

NM_000504.4

p.C390F

c.1169G>T

1 paper

NM_000504.4

p.S374P

c.1120T>C