Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000504.4

p.S394T

c.1181G>C

Surrounding Variants

2 papers

NM_000504.4

p.S394R

c.1180A>C

2 papers

NM_000504.4

p.S394R

c.1182C>A

2 papers

NM_000504.4

p.S394R

c.1182C>G

1 paper

NM_000504.4

p.S394S

c.1182C>T

1 paper

NM_000504.4

p.S393Y

c.1178C>A

1 paper

NM_000504.4

p.S393P

c.1177T>C

1 paper

NM_000504.4

p.F396fs

c.1186_1187fs

1 paper

NM_000504.4

p.F396Y

c.1187T>A

1 paper

NM_000504.4

p.F396C

c.1187T>G

1 paper

NM_000504.4

p.F396_Q400delFs

c.1188_1200del13

5 papers

NM_000504.4

p.C390F

c.1169G>T

1 paper

NM_000504.4

p.R387insFs

c.1160_1161insT