Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000504.4

p.Q411*

c.1231C>T

Surrounding Variants

1 paper

NM_000504.4

p.T409I

c.1226C>T

1 paper

NM_000504.4

p.D413N

c.1237G>A

4 papers

NM_000504.4

p.D408N

c.1222G>A

1 paper

NM_000504.4

p.D408del1

c.1222_1223delGAC

8 papers

NM_000504.4

p.G406S

c.1216G>A

1 paper

NM_000504.4

p.Q416P

c.1247A>C

4 papers

NM_000504.4

p.Q416L

c.1247A>T

1 paper

NM_000504.4

p.A405A

c.1215C>T

2 papers

NM_000504.4

p.A405T

c.1213G>A

1 paper

NM_000504.4

p.D418H

c.1252G>C

5 papers

NM_000504.4

p.C404R

c.1210T>C

1 paper

NM_000504.4

p.D418G

c.1253A>G