Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000504.4

p.V437I

c.1309G>A

Surrounding Variants

1 paper

NM_000504.4

p.S438N

c.1313G>A

5 papers

NM_000504.4

p.G435S

c.1303G>A

1 paper

NM_000504.4

p.T434fs

c.1300_1301fs

1 paper

NM_000504.4

p.V433insFs

c.1298dupT

1 paper

NM_000504.4

p.G442S

c.1324G>A

4 papers

NM_000504.4

p.Y431_F432insFs

c.1293_1294insG

1 paper

NM_000504.4

p.G442D

c.1325G>A

1 paper

NM_000504.4

p.G442V

c.1325G>T

1 paper

NM_000504.4

p.A444_R445delFs

c.1330_1334del5

1 paper

NM_000504.4

p.A444T

c.1330G>A

1 paper

NM_000504.4

p.R445G

c.1333C>G

4 papers

NM_000504.4

p.R445C

c.1333C>T