Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000504.4

p.Y449D

c.1345T>G

Surrounding Variants

2 papers

NM_000504.4

p.Y449S

c.1346A>C

1 paper

NM_000504.4

p.K448N

c.1344G>C

1 paper

NM_000504.4

p.K448N

c.1344G>T

4 papers

NM_000504.4

p.G450R

c.1348G>A

4 papers

NM_000504.4

p.G450R

c.1348G>C

1 paper

NM_000504.4

p.G450W

c.1348G>T

4 papers

NM_000504.4

p.I451L

c.1351A>C

1 paper

NM_000504.4

p.I451F

c.1351A>T

1 paper

NM_000504.4

p.Y452N

c.1354T>A

2 papers

NM_000504.4

p.R445H

c.1334G>A

1 paper

NM_000504.4

p.R445G

c.1333C>G

4 papers

NM_000504.4

p.R445C

c.1333C>T