Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000504.4

p.W461C

c.1383G>T

Surrounding Variants

2 papers

NM_000504.4

p.W461*

c.1383G>A

2 papers

NM_000504.4

p.W461C

c.1383G>C

2 papers

NM_000504.4

p.W461*

c.1382G>A

1 paper

NM_000504.4

p.W461R

c.1381T>A

1 paper

NM_000504.4

p.W461R

c.1381T>C

1 paper

NM_000504.4

p.K460del1

c.1378_1380delAAG

1 paper

NM_000504.4

p.S465P

c.1393T>C

1 paper

NM_000504.4

p.F458I

c.1372T>A

1 paper

NM_000504.4

p.R469K

c.1406G>A

1 paper

NM_000504.4

p.G470D

c.1409G>A

1 paper

NM_000504.4

p.Y452N

c.1354T>A

4 papers

NM_000504.4

p.I451L

c.1351A>C