Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000504.4

p.L487F

c.1461A>T

Surrounding Variants

1 paper

NM_000504.4

p.L487F

c.1461A>C

1 paper

NM_000504.4

p.*489insFs

c.1466dupG

1 paper

NM_000504.4

p.S484Y

c.1451C>A

1 paper

NM_000504.4

p.E480*

c.1438G>T

1 paper

NM_000504.4

p.P479S

c.1435C>T

1 paper

NM_000504.4

p.H477_A478delFs

c.1430_1434del5

1 paper

NM_000504.4

p.G470D

c.1409G>A

1 paper

NM_000504.4

p.R469K

c.1406G>A

1 paper

NM_000504.4

p.S465P

c.1393T>C

2 papers

NM_000504.4

p.W461*

c.1383G>A

2 papers

NM_000504.4

p.W461C

c.1383G>C

2 papers

NM_000504.4

p.W461C

c.1383G>T