Varaico: Literature-Extracted Genetic Variants

Gene:F2R
Variant:p.D58E

F2R

297 papers

RefSeq Summary

Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled...

Pfam Domains

7tm_1aa 119–371UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

coagulation factor II thrombin receptor

HGNC Alias Symbols

TR; CF2R; PAR1; PAR-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001992.5
p.D58E
c.174T>A
Surrounding Variants
1 paper
NM_001992.5
p.D58A
c.173A>C
1 paper
NM_001992.5
p.E57V
c.170A>T
2 papers
NM_001992.5
p.E57K
c.169G>A
1 paper
NM_001992.5
p.W56S
c.167G>C
1 paper
NM_001992.5
p.S64G
c.190A>G
1 paper
NM_001992.5
p.S64S
c.192T>C
1 paper
NM_001992.5
p.E68K
c.202G>A
1 paper
NM_001992.5
p.Y69N
c.205T>A
1 paper
NM_001992.5
p.Y69F
c.206A>T
1 paper
NM_001992.5
p.N47D
c.139A>G
1 paper
NM_001992.5
p.R46G
c.136A>G
1 paper
NM_001992.5
p.L45P
c.134T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."