Varaico: Literature-Extracted Genetic Variants

Gene:F2R
Variant:p.L237M

F2R

297 papers

RefSeq Summary

Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled...

Pfam Domains

7tm_1aa 119–371UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

coagulation factor II thrombin receptor

HGNC Alias Symbols

TR; CF2R; PAR1; PAR-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001992.5
p.L237M
c.709C>A
Surrounding Variants
1 paper
NM_001992.5
p.L238_L239insG
c.712_716ins3
1 paper
NM_001992.5
p.L238L
c.714C>A
1 paper
NM_001992.5
p.K240E
c.718A>G
1 paper
NM_001992.5
p.K240R
c.719A>G
1 paper
NM_001992.5
p.E241Q
c.721G>C
1 paper
NM_001992.5
p.E241A
c.722A>C
1 paper
NM_001992.5
p.V246M
c.736G>A
1 paper
NM_001992.5
p.W227L
c.680G>T
1 paper
NM_001992.5
p.A225V
c.674C>T
1 paper
NM_001992.5
p.A225T
c.673G>A
1 paper
NM_001992.5
p.L249L
c.747C>G
1 paper
NM_001992.5
p.I251L
c.751A>C
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