Varaico: Literature-Extracted Genetic Variants

Gene:F2R
Variant:p.Y266C

F2R

297 papers

RefSeq Summary

Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled...

Pfam Domains

7tm_1aa 119–371UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

coagulation factor II thrombin receptor

HGNC Alias Symbols

TR; CF2R; PAR1; PAR-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_001992.5
p.Y266C
c.797A>G
Surrounding Variants
1 paper
NM_001992.5
p.G265A
c.794G>C
1 paper
NM_001992.5
p.A268P
c.802G>C
2 papers
NM_001992.5
p.E264A
c.791A>C
1 paper
NM_001992.5
p.Y269C
c.806A>G
4 papers
NM_001992.5
p.Y269Y
c.807C>T
2 papers
NM_001992.5
p.L263F
c.787C>T
1 paper
NM_001992.5
p.Y270delFs
c.808_809delTA
1 paper
NM_001992.5
p.T261I
c.782C>T
1 paper
NM_001992.5
p.T261A
c.781A>G
2 papers
NM_001992.5
p.E260A
c.779A>C
3 papers
NM_001992.5
p.N259S
c.776A>G
1 paper
NM_001992.5
p.A273V
c.818C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."