Varaico: Literature-Extracted Genetic Variants

FARSB

87 papers

RefSeq Summary

This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalyti...

Pfam Domains

PhetRS_B1aa 1–90UCSCPhe-tRNA synthetase beta subunit B1 domain

B3_4aa 106–279UCSCB3/4 domain

B5aa 308–374UCSCtRNA synthetase B5 domain

tRNA_synthFbetaaa 377–585UCSCPhenylalanyl tRNA synthetase beta chain CLM domain

Gene Aliases

HGNC Name

phenylalanyl-tRNA synthetase subunit beta

HGNC Previous Symbol

FARSLB

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005687.5

p.V585A

c.1754T>C

Surrounding Variants

6 papers

NM_005687.5

p.V585I

c.1753G>A

1 paper

NM_005687.5

p.N584S

c.1751A>G

3 papers

NM_005687.5

p.H565R

c.1694A>G

1 paper

NM_005687.5

p.G562V

c.1685G>T

1 paper

NM_005687.5

p.G562R

c.1684G>A

1 paper

NM_005687.5

p.L561F

c.1681C>T

1 paper

NM_005687.5

p.G559R

c.1675G>A

1 paper

NM_005687.5

p.V558A

c.1673T>C

1 paper

NM_005687.5

p.G540R

c.1618G>C

1 paper

NM_005687.5

p.G540R

c.1618G>A