Varaico: Literature-Extracted Genetic Variants

FARSB

87 papers

RefSeq Summary

This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalyti...

Pfam Domains

PhetRS_B1aa 1–90UCSCPhe-tRNA synthetase beta subunit B1 domain

B3_4aa 106–279UCSCB3/4 domain

B5aa 308–374UCSCtRNA synthetase B5 domain

tRNA_synthFbetaaa 377–585UCSCPhenylalanyl tRNA synthetase beta chain CLM domain

Gene Aliases

HGNC Name

phenylalanyl-tRNA synthetase subunit beta

HGNC Previous Symbol

FARSLB

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005687.5

p.E113V

c.338A>T

Surrounding Variants

1 paper

NM_005687.5

p.I110I

c.330C>A

2 papers

NM_005687.5

p.R98Q

c.293G>A

1 paper

NM_005687.5

p.P119S

c.355C>T

1 paper

NM_005687.5

p.A123T

c.367G>A

1 paper

NM_005687.5

p.A124E

c.371C>A

2 papers

NM_005687.5

p.R127H

c.380G>A

1 paper

NM_005687.5

p.R135Q

c.404G>A

2 papers

NM_005687.5

p.Q143R

c.428A>G

1 paper

NM_005687.5

p.L84R

c.251T>G

1 paper

NM_005687.5

p.C76R

c.226T>C

1 paper

NM_005687.5

p.L74F

c.220C>T

1 paper

NM_005687.5

p.V61I

c.181G>A