Varaico: Literature-Extracted Genetic Variants

FAS

972 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of program...

Pfam Domains

TNFR_c6aa 85–127UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 129–165UCSCTNFR/NGFR cysteine-rich region

Deathaa 245–329UCSCDeath domain

Gene Aliases

HGNC Name

Fas cell surface death receptor

HGNC Previous Symbols

FAS1; APT1; TNFRSF6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000043.6

p.A70fs

c.208_209fs

Surrounding Variants

1 paper

NM_000043.6

p.A70V

c.209C>T

1 paper

NM_000043.6

p.K69T

c.206A>C

1 paper

NM_000043.6

p.R71G

c.211A>G

1 paper

NM_000043.6

p.R71W

c.211A>T

1 paper

NM_000043.6

p.R68S

c.204G>T

1 paper

NM_000043.6

p.R68insFs

c.203dupG

2 papers

NM_000043.6

p.R68G

c.202A>G

1 paper

NM_000043.6

p.R68delFs

c.203delG

1 paper

NM_000043.6

p.D72N

c.214G>A

1 paper

NM_000043.6

p.D72G

c.215A>G

1 paper

NM_000043.6

p.E67fs

c.199_200fs

2 papers

NM_000043.6

p.E67*

c.199G>T