Varaico: Literature-Extracted Genetic Variants

FAS

972 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of program...

Pfam Domains

TNFR_c6aa 85–127UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 129–165UCSCTNFR/NGFR cysteine-rich region

Deathaa 245–329UCSCDeath domain

Gene Aliases

HGNC Name

Fas cell surface death receptor

HGNC Previous Symbols

FAS1; APT1; TNFRSF6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000043.6

p.S99S

c.297C>T

Surrounding Variants

1 paper

NM_000043.6

p.S98fs

c.292_293fs

4 papers

NM_000043.6

p.R102G

c.304A>G

1 paper

NM_000043.6

p.R102S

c.306A>T

1 paper

NM_000043.6

p.H96Q

c.288T>A

1 paper

NM_000043.6

p.H96R

c.287A>G

1 paper

NM_000043.6

p.H96Y

c.286C>T

12 papers

NM_000043.6

p.R103K

c.308G>A

2 papers

NM_000043.6

p.R103S

c.309A>C

1 paper

NM_000043.6

p.R103S

c.309A>T

1 paper

NM_000043.6

p.A95A

c.285C>A

1 paper

NM_000043.6

p.C104S

c.310T>A

3 papers

NM_000043.6

p.C104R

c.310T>C