Varaico: Literature-Extracted Genetic Variants

FAS

972 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of program...

Pfam Domains

TNFR_c6aa 85–127UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 129–165UCSCTNFR/NGFR cysteine-rich region

Deathaa 245–329UCSCDeath domain

Gene Aliases

HGNC Name

Fas cell surface death receptor

HGNC Previous Symbols

FAS1; APT1; TNFRSF6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

13 papers

NM_000043.6

p.D260V

c.779A>T

Surrounding Variants

10 papers

NM_000043.6

p.D260G

c.779A>G

9 papers

NM_000043.6

p.D260N

c.778G>A

3 papers

NM_000043.6

p.D260H

c.778G>C

5 papers

NM_000043.6

p.D260Y

c.778G>T

4 papers

NM_000043.6

p.D260E

c.780T>A

4 papers

NM_000043.6

p.D260E

c.780T>G

8 papers

NM_000043.6

p.E261K

c.781G>A

1 paper

NM_000043.6

p.E261V

c.782A>T

5 papers

NM_000043.6

p.I259T

c.776T>C

1 paper

NM_000043.6

p.E261D

c.783G>C

1 paper

NM_000043.6

p.E261D

c.783G>T

1 paper

NM_000043.6

p.I262fs

c.784_785fs