Varaico: Literature-Extracted Genetic Variants

FAS

972 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of program...

Pfam Domains

TNFR_c6aa 85–127UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 129–165UCSCTNFR/NGFR cysteine-rich region

Deathaa 245–329UCSCDeath domain

Gene Aliases

HGNC Name

Fas cell surface death receptor

HGNC Previous Symbols

FAS1; APT1; TNFRSF6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000043.6

p.N264K

c.792T>G

Surrounding Variants

2 papers

NM_000043.6

p.N264K

c.792T>A

2 papers

NM_000043.6

p.D265H

c.793G>C

10 papers

NM_000043.6

p.D265G

c.794A>G

2 papers

NM_000043.6

p.N264D

c.790A>G

2 papers

NM_000043.6

p.D265V

c.794A>T

3 papers

NM_000043.6

p.D265E

c.795C>A

3 papers

NM_000043.6

p.D265E

c.795C>G

1 paper

NM_000043.6

p.D265D

c.795C>T

1 paper

NM_000043.6

p.K263T

c.788A>C

1 paper

NM_000043.6

p.K263R

c.788A>G

4 papers

NM_000043.6

p.N266S

c.797A>G

1 paper

NM_000043.6

p.I262M

c.786C>G