Varaico: Literature-Extracted Genetic Variants

Gene:FASLG
Variant:p.A24D

FASLG

646 papers

RefSeq Summary

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signa...

Pfam Domains

TNFaa 160–281UCSCTNF(Tumour Necrosis Factor) family

Gene Aliases

HGNC Name

Fas ligand

HGNC Previous Symbols

APT1LG1; TNFSF6

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000639.3
p.A24D
c.71C>A
Surrounding Variants
1 paper
NM_000639.3
p.A24V
c.71C>T
1 paper
NM_000639.3
p.P26T
c.76C>A
1 paper
NM_000639.3
p.S21S
c.63T>A
1 paper
NM_000639.3
p.A19S
c.55G>T
2 papers
NM_000639.3
p.S17G
c.49A>G
2 papers
NM_000639.3
p.P31P
c.93C>T
1 paper
NM_000639.3
p.C32S
c.94T>A
1 paper
NM_000639.3
p.C32Y
c.95G>A
1 paper
NM_000639.3
p.V15A
c.44T>C
1 paper
NM_000639.3
p.W14R
c.40T>A
2 papers
NM_000639.3
p.S35C
c.104C>G
2 papers
NM_000639.3
p.V36A
c.107T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."