Varaico: Literature-Extracted Genetic Variants

Gene:FASLG
Variant:p.F87fs

FASLG

646 papers

RefSeq Summary

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signa...

Pfam Domains

TNFaa 160–281UCSCTNF(Tumour Necrosis Factor) family

Gene Aliases

HGNC Name

Fas ligand

HGNC Previous Symbols

APT1LG1; TNFSF6

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_000639.3
p.F87fs
c.259_260fs
Surrounding Variants
3 papers
NM_000639.3
p.F87L
c.259T>C
1 paper
NM_000639.3
p.M86I
c.258G>A
3 papers
NM_000639.3
p.F87delFs
c.259delT
2 papers
NM_000639.3
p.M86V
c.256A>G
1 paper
NM_000639.3
p.F88fs
c.262_263fs
3 papers
NM_000639.3
p.F88S
c.263T>C
1 paper
NM_000639.3
p.V85E
c.254T>A
1 paper
NM_000639.3
p.L84_M86delFs
c.252_256del5
1 paper
NM_000639.3
p.L83V
c.247C>G
1 paper
NM_000639.3
p.L91L
c.273G>C
1 paper
NM_000639.3
p.C82R
c.244T>C
1 paper
NM_000639.3
p.A93V
c.278C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."