Varaico: Literature-Extracted Genetic Variants

Gene:FASLG
Variant:p.K178insFs

FASLG

646 papers

RefSeq Summary

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signa...

Pfam Domains

TNFaa 160–281UCSCTNF(Tumour Necrosis Factor) family

Gene Aliases

HGNC Name

Fas ligand

HGNC Previous Symbols

APT1LG1; TNFSF6

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000639.3
p.K178insFs
c.533_534insG
Surrounding Variants
1 paper
NM_000639.3
p.K178E
c.532A>G
2 papers
NM_000639.3
p.K177R
c.530A>G
1 paper
NM_000639.3
p.G180_L181insFs
c.540_541insG
1 paper
NM_000639.3
p.L181P
c.542T>C
1 paper
NM_000639.3
p.V174fs
c.520_521fs
1 paper
NM_000639.3
p.G173A
c.518G>C
2 papers
NM_000639.3
p.E185del1
c.553_554delGAA
1 paper
NM_000639.3
p.L171F
c.511C>T
1 paper
NM_000639.3
p.G187W
c.559G>T
1 paper
NM_000639.3
p.G187E
c.560G>A
1 paper
NM_000639.3
p.G167R
c.499G>A
1 paper
NM_000639.3
p.G167R
c.499G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."