Varaico: Literature-Extracted Genetic Variants

FASTK

125 papers

RefSeq Summary

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to ...

Pfam Domains

FAST_1aa 277–346UCSCFAST kinase-like protein, subdomain 1

FAST_2aa 355–444UCSCFAST kinase-like protein, subdomain 2

RAPaa 481–536UCSCRAP domain

Gene Aliases

HGNC Name

Fas activated serine/threonine kinase

HGNC Alias Symbol

FAST

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006712.5

p.D490N

c.1468G>A

Surrounding Variants

1 paper

NM_006712.5

p.H486Y

c.1456C>T

1 paper

NM_006712.5

p.R484H

c.1451G>A

1 paper

NM_006712.5

p.E483*

c.1447G>T

1 paper

NM_006712.5

p.S497W

c.1490C>G

1 paper

NM_006712.5

p.A499S

c.1495G>T

1 paper

NM_006712.5

p.R503R

c.1509G>C

1 paper

NM_006712.5

p.Y510F

c.1529A>T

1 paper

NM_006712.5

p.L512I

c.1534C>A

1 paper

NM_006712.5

p.P514L

c.1541C>T

1 paper

NM_006712.5

p.P514P

c.1542G>C

1 paper

NM_006712.5

p.P514P

c.1542G>A

1 paper

NM_006712.5

p.A474V

c.1421C>T