Varaico: Literature-Extracted Genetic Variants

FBXW11

92 papers

RefSeq Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin pr...

Pfam Domains

Beta-TrCP_Daa 78–116UCSCD domain of beta-TrCP

Beta-TrCP_Daa 99–137UCSCD domain of beta-TrCP

F-box-likeaa 129–170UCSCF-box-like

WD40aa 230–266UCSCWD domain, G-beta repeat

Gene Aliases

HGNC Name

F-box and WD repeat domain containing 11

HGNC Previous Symbol

FBXW1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_001378974.1

p.L170L

c.508C>T

Surrounding Variants

1 paper

NM_001378974.1

p.L170V

c.508C>G

1 paper

NM_001378974.1

p.S158S

c.474G>A

1 paper

NM_001378974.1

p.I152M

c.456A>G

1 paper

NM_012300.3

p.R170*

c.508C>T

1 paper

NM_012300.3

p.R170G

c.508C>G

1 paper

NM_001378974.1

p.P217insFs

c.650_651insT

1 paper

NM_001378974.1

p.I233V

c.697A>G

1 paper

NM_001378974.1

p.I240L

c.718A>C

2 papers

NM_012300.3

p.G242R

c.724G>C

1 paper

NM_001378974.1

p.Y265H

c.793T>C

2 papers

NM_001378974.1

p.R279*

c.835C>T