Varaico: Literature-Extracted Genetic Variants

FBXW4

30 papers

RefSeq Summary

This gene is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. In mouse, a highly ...

Pfam Domains

F-box-likeaa 28–74UCSCF-box-like

F-box-likeaa 183–229UCSCF-box-like

WD40aa 192–228UCSCWD domain, G-beta repeat

WD40aa 326–365UCSCWD domain, G-beta repeat

WD40aa 347–383UCSCWD domain, G-beta repeat

WD40aa 481–520UCSCWD domain, G-beta repeat

Gene Aliases

HGNC Name

F-box and WD repeat domain containing 4

HGNC Previous Symbol

SHFM3

Papers

RefSeq ID

Protein change

DNA change

1–12 of 27 variants

2 papers

NM_022039.4

p.N12_G14del0

c.35_40del6

2 papers

NM_022039.4

p.K35_K40del6

c.103_119del18

2 papers

NM_022039.4

p.E168del1

c.502_503delCTC

2 papers

NM_022039.4

p.K380_V381Splc

c.1141-2A>C

2 papers

NM_022039.4

p.N503_L505del3

c.1507_1514del9

1 paper

NM_022039.4

p.Q4_G5del1

c.12_14delCCC

1 paper

NM_022039.4

p.G11insFs

c.31dupG

1 paper

NM_022039.4

p.G13_G14del1

c.38_40delCGC

1 paper

NM_022039.4

p.N12_G14del3

c.34_41del9

1 paper

NM_022039.4

p.P15ins1

c.44_45insGGC

1 paper

NM_022039.4

p.K38T

c.113A>C

1 paper

NM_022039.4

p.G39E

c.116G>A