Varaico: Literature-Extracted Genetic Variants

Gene:FDXR
Variant:p.Q442L

FDXR

2,127 papers

RefSeq Summary

This gene encodes a mitochondrial flavoprotein that initiates electron transport for cytochromes P450 receiving electrons from NADPH. Multiple alternatively spliced transcript variants have been found...

Pfam Domains

NAD_binding_8aa 43–107UCSCNAD(P)-binding Rossmann-like domain

Gene Aliases

HGNC Name

ferredoxin reductase

HGNC Previous Symbol

ADXR

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_024417.5
p.Q442L
c.1325A>T
Surrounding Variants
2 papers
NM_024417.5
p.A443S
c.1327G>T
3 papers
NM_024417.5
p.A443T
c.1327G>A
1 paper
NM_001258015.3
p.A403V
c.1208C>T
1 paper
NM_024417.5
p.Q442delFs
c.1326delC
1 paper
NM_024417.5
p.L444P
c.1331T>C
1 paper
NM_024417.5
p.A439_A440delFs
c.1317_1318delCT
2 papers
NM_024417.5
p.Y438_A439delFs
c.1314_1315delCG
1 paper
NM_024417.5
p.L445P
c.1334T>C
1 paper
NM_024417.5
p.L445_S446insFs
c.1335_1336insGG
3 papers
NM_024417.5
p.G437C
c.1309G>T
2 papers
NM_024417.5
p.G437R
c.1309G>C
4 papers
NM_024417.5
p.G437S
c.1309G>A
NM_001258015.3
p.G397S
c.1189G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."