Varaico: Literature-Extracted Genetic Variants

Gene:FEN1
Variant:p.D86A

FEN1

291 papers

RefSeq Summary

The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this pro...

Pfam Domains

XPG_Naa 1–107UCSCXPG N-terminal domain
XPG_Iaa 149–233UCSCXPG I-region

Gene Aliases

HGNC Name

flap structure-specific endonuclease 1

HGNC Alias Symbols

FEN-1; MF1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
5 papers
NM_004111.6
p.D86A
c.257A>C
Surrounding Variants
1 paper
NM_004111.6
p.D86G
c.257A>G
2 papers
NM_004111.6
p.D86N
c.256G>A
1 paper
NM_004111.6
p.Y83H
c.247T>C
1 paper
NM_004111.6
p.P90delFs
c.270delA
1 paper
NM_004111.6
p.L92F
c.274C>T
1 paper
NM_004111.6
p.I79M
c.237C>G
1 paper
NM_004111.6
p.N77H
c.229A>C
1 paper
NM_004111.6
p.E76fs
c.226_227fs
2 papers
NM_004111.6
p.L97P
c.290T>C
1 paper
NM_004111.6
p.A98T
c.292G>A
1 paper
NM_004111.6
p.K99K
c.297A>G
1 paper
NM_004111.6
p.R73G
c.217C>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."