Varaico: Literature-Extracted Genetic Variants

FER

228 papers

RefSeq Summary

The protein encoded by this gene is a member of the FPS/FES family of non-transmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the c...

Pfam Domains

FCHaa 10–87UCSCFes/CIP4, and EFC/F-BAR homology domain

SH2aa 460–531UCSCSH2 domain

PK_Tyr_Ser-Thraa 563–814UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

FER tyrosine kinase

HGNC Alias Symbols

TYK3; PPP1R74

Papers

RefSeq ID

Protein change

DNA change

1–12 of 126 variants

5 papers

NM_005246.4

p.G4G

c.12G>C

2 papers

NM_005246.4

p.K29insFs

c.86_87insC

2 papers

NM_005246.4

p.L204F

c.610C>T

2 papers

NM_005246.4

p.L439V

c.1315C>G

2 papers

NM_005246.4

p.E472D

c.1416A>T

2 papers

NM_005246.4

p.E567E

c.1701A>G

2 papers

NM_005246.4

p.K583_D584insFs

c.1749_1750insT

2 papers

NM_005246.4

p.L612F

c.1834C>T

2 papers

NM_005246.4

p.K663Q

c.1987A>C

2 papers

NM_005246.4

p.E787E

c.2361G>A

1 paper

NM_005246.4

p.M1R

c.2T>G

1 paper

NM_005246.4

p.M1I

c.3G>A