Varaico: Literature-Extracted Genetic Variants

FER

228 papers

RefSeq Summary

The protein encoded by this gene is a member of the FPS/FES family of non-transmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the c...

Pfam Domains

FCHaa 10–87UCSCFes/CIP4, and EFC/F-BAR homology domain

SH2aa 460–531UCSCSH2 domain

PK_Tyr_Ser-Thraa 563–814UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

FER tyrosine kinase

HGNC Alias Symbols

TYK3; PPP1R74

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005246.4

p.I428Fs

c.1284delinsAGFs

Surrounding Variants

1 paper

NM_005246.4

p.R425C

c.1273C>T

2 papers

NM_005246.4

p.L439V

c.1315C>G

1 paper

NM_005246.4

p.K415K

c.1245G>A

1 paper

NM_005246.4

p.K415M

c.1244A>T

2 papers

NM_005246.4

p.E472D

c.1416A>T

1 paper

NM_005246.4

p.K476insFs

c.1428dupA

1 paper

NM_005246.4

p.K475K

c.1425A>G