Varaico: Literature-Extracted Genetic Variants

FER

228 papers

RefSeq Summary

The protein encoded by this gene is a member of the FPS/FES family of non-transmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the c...

Pfam Domains

FCHaa 10–87UCSCFes/CIP4, and EFC/F-BAR homology domain

SH2aa 460–531UCSCSH2 domain

PK_Tyr_Ser-Thraa 563–814UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

FER tyrosine kinase

HGNC Alias Symbols

TYK3; PPP1R74

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005246.4

p.Q526*

c.1576C>T

Surrounding Variants

1 paper

NM_005246.4

p.I528T

c.1583T>C

1 paper

NM_005246.4

p.Y532H

c.1594T>C

1 paper

NM_005246.4

p.T534delFs

c.1601delC

1 paper

NM_005246.4

p.E517K

c.1549G>A

1 paper

NM_005246.4

p.R515Q

c.1544G>A

1 paper

NM_005246.4

p.K475K

c.1425A>G

1 paper

NM_005246.4

p.K476insFs

c.1428dupA

2 papers

NM_005246.4

p.E472D

c.1416A>T