Varaico: Literature-Extracted Genetic Variants

FER

228 papers

RefSeq Summary

The protein encoded by this gene is a member of the FPS/FES family of non-transmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the c...

Pfam Domains

FCHaa 10–87UCSCFes/CIP4, and EFC/F-BAR homology domain

SH2aa 460–531UCSCSH2 domain

PK_Tyr_Ser-Thraa 563–814UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

FER tyrosine kinase

HGNC Alias Symbols

TYK3; PPP1R74

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005246.4

p.K583_D584insFs

c.1749_1750insT

Surrounding Variants

1 paper

NM_005246.4

p.T581S

c.1741A>T

1 paper

NM_005246.4

p.T586I

c.1757C>T

1 paper

NM_005246.4

p.G580delFs

c.1740delC

1 paper

NM_005246.4

p.K579_T592ins4

c.1736_1774dup39

1 paper

NM_005246.4

p.K591R

c.1772A>G

1 paper

NM_005246.4

p.F574_T586ins4

c.1721_1756dup36

1 paper

NM_005246.4

p.L601F

c.1803G>C

1 paper

NM_005246.4

p.L601F

c.1803G>T

1 paper

NM_005246.4

p.K604R

c.1811A>G

2 papers

NM_005246.4

p.L612F

c.1834C>T

1 paper

NM_005246.4

p.L612_G625ins4

c.1836_1874dup39

1 paper

NM_005246.4

p.K613_V626insFs

c.1838_1877dup40