Varaico: Literature-Extracted Genetic Variants

FER

228 papers

RefSeq Summary

The protein encoded by this gene is a member of the FPS/FES family of non-transmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the c...

Pfam Domains

FCHaa 10–87UCSCFes/CIP4, and EFC/F-BAR homology domain

SH2aa 460–531UCSCSH2 domain

PK_Tyr_Ser-Thraa 563–814UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

FER tyrosine kinase

HGNC Alias Symbols

TYK3; PPP1R74

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005246.4

p.L612F

c.1834C>T

Surrounding Variants

1 paper

NM_005246.4

p.L612_G625ins4

c.1836_1874dup39

1 paper

NM_005246.4

p.K613_V626insFs

c.1838_1877dup40

1 paper

NM_005246.4

p.Q614_K622ins3

c.1842_1865dup24

1 paper

NM_005246.4

p.H617insFs

c.1850dupA

1 paper

NM_005246.4

p.N619_G625ins2

c.1855_1875dup21

1 paper

NM_005246.4

p.K622ins1

c.1865_1866insGAA

1 paper

NM_005246.4

p.T628I

c.1883C>T

1 paper

NM_005246.4

p.Q629insFs

c.1886dupA

1 paper

NM_005246.4

p.Q629H

c.1887A>C

1 paper

NM_005246.4

p.Q629H

c.1887A>T

1 paper

NM_005246.4

p.Y634F

c.1901A>T

1 paper

NM_005246.4

p.I636N

c.1907T>A