Varaico: Literature-Extracted Genetic Variants

FER

228 papers

RefSeq Summary

The protein encoded by this gene is a member of the FPS/FES family of non-transmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the c...

Pfam Domains

FCHaa 10–87UCSCFes/CIP4, and EFC/F-BAR homology domain

SH2aa 460–531UCSCSH2 domain

PK_Tyr_Ser-Thraa 563–814UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

FER tyrosine kinase

HGNC Alias Symbols

TYK3; PPP1R74

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005246.4

p.D654N

c.1960G>A

Surrounding Variants

1 paper

NM_005246.4

p.K653K

c.1959G>A

1 paper

NM_005246.4

p.R651R

c.1953G>A

2 papers

NM_005246.4

p.K663Q

c.1987A>C

1 paper

NM_005246.4

p.D644N

c.1930G>A

1 paper

NM_005246.4

p.N679Y

c.2035A>T