Varaico: Literature-Extracted Genetic Variants

FER

228 papers

RefSeq Summary

The protein encoded by this gene is a member of the FPS/FES family of non-transmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the c...

Pfam Domains

FCHaa 10–87UCSCFes/CIP4, and EFC/F-BAR homology domain

SH2aa 460–531UCSCSH2 domain

PK_Tyr_Ser-Thraa 563–814UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

FER tyrosine kinase

HGNC Alias Symbols

TYK3; PPP1R74

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005246.4

p.M764T

c.2291T>C

Surrounding Variants

1 paper

NM_005246.4

p.G757E

c.2270G>A

1 paper

NM_005246.4

p.G776Splc

c.2326+3G>A

1 paper

NM_005246.4

p.V743M

c.2227G>A

1 paper

NM_005246.4

p.S738T

c.2213G>C

1 paper

NM_005246.4

p.A781V

c.2342C>T

2 papers

NM_005246.4

p.E787E

c.2361G>A

1 paper

NM_005246.4

p.I792T

c.2375T>C

1 paper

NM_005246.4

p.R804C

c.2410C>T

1 paper

NM_005246.4

p.A728S

c.2182G>T

1 paper

NM_005246.4

p.P723L

c.2168C>T