Varaico: Literature-Extracted Genetic Variants

FES

72 papers

RefSeq Summary

This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity...

Pfam Domains

FCHaa 12–89UCSCFes/CIP4, and EFC/F-BAR homology domain

SH2aa 460–530UCSCSH2 domain

PK_Tyr_Ser-Thraa 561–814UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

FES proto-oncogene, tyrosine kinase

HGNC Alias Symbol

FPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_002005.4

p.K590E

c.1768A>G

Surrounding Variants

1 paper

NM_002005.4

p.R593Q

c.1778G>A

1 paper

NM_002005.4

p.T595Fs

c.1783delinsGCFs

1 paper

NM_002005.4

p.D583Fs

c.1747delinsGCFs

1 paper

NM_002005.4

p.L580L

c.1738C>T

1 paper

NM_002005.4

p.A653_R654Fs

c.1958_1960delinsGGGACCCFs

1 paper

NM_002005.4

p.R687W

c.2059C>T

1 paper

NM_002005.4

p.F702C

c.2105T>G

1 paper

NM_002005.4

p.M704V

c.2110A>G

1 paper

NM_002005.4

p.A709A

c.2127C>T

1 paper

NM_002005.4

p.Y713F

c.2138A>T

1 paper

NM_002005.4

p.G717G

c.2151G>T

1 paper

NM_002005.4

p.T538N

c.1613C>A