Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

1–12 of 902 variants

32 papers

NM_021871.4

p.R35H

c.104G>A

32 papers

NM_021871.4

p.E170_V171Splc

c.510+1G>T

27 papers

NM_021871.4

p.R35C

c.103C>T

26 papers

NM_021871.4

p.T331A

c.991A>G

20 papers

NM_021871.4

p.V34L

c.100G>T

20 papers

NM_021871.4

p.V34L

c.100G>C

16 papers

NM_021871.4

p.E545V

c.1634A>T

13 papers

NM_021871.4

p.R38G

c.112A>G

12 papers

NM_021871.4

p.R38S

c.114G>T

12 papers

NM_021871.4

p.R38S

c.114G>C

12 papers

NM_021871.4

p.R168*

c.502C>T

10 papers

NM_021871.4

p.W334*

c.1001G>A