Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_021871.4

p.G574delins

c.1720_1721delinsTT

Surrounding Variants

8 papers

NM_021871.4

p.R573L

c.1718G>T

3 papers

NM_021871.4

p.R573H

c.1718G>A

1 paper

NM_021871.4

p.K575insFs

c.1724_1725insT

8 papers

NM_021871.4

p.R573C

c.1717C>T

2 papers

NM_021871.4

p.K575fs

c.1723_1724fs

2 papers

NM_021871.4

p.K575delFs

c.1725delT

7 papers

NM_021871.4

p.P571H

c.1712C>A

1 paper

NM_021871.4

p.S578G

c.1732A>G

1 paper

NM_021871.4

p.Y579F

c.1736A>T

1 paper

NM_021871.4

p.Y579Fs

c.1736_1737delinsTTGGAATTTTFs

1 paper

NM_021871.4

p.S580I

c.1739G>T

1 paper

NM_021871.4

p.I567V

c.1699A>G