Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.G552S

c.1654G>A

Surrounding Variants

2 papers

NM_021871.4

p.S551delFs

c.1653delA

1 paper

NM_021871.4

p.S546_E550del0

c.1636_1650del15

1 paper

NM_021871.4

p.G552fs

c.1654_1655fs

1 paper

NM_021871.4

p.S551F

c.1652C>T

4 papers

NM_021871.4

p.S551C

c.1652C>G

1 paper

NM_021871.4

p.E550_S551insFs

c.1650_1651insCA

1 paper

NM_021871.4

p.E550insFs

c.1649_1650insCA

1 paper

NM_021871.4

p.E550K

c.1648G>A

1 paper

NM_021871.4

p.G548D

c.1643G>A

1 paper

NM_021871.4

p.R547S

c.1641G>C

1 paper

NM_021871.4

p.T555delFs

c.1665delT

5 papers

NM_021871.4

p.R547delFs

c.1639delT