Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_021871.4

p.D496N

c.1486G>A

Surrounding Variants

1 paper

NM_021871.4

p.D496Y

c.1486G>T

1 paper

NM_021871.4

p.M495insFs

c.1483dupA

1 paper

NM_021871.4

p.L497V

c.1489T>G

1 paper

NM_021871.4

p.M495fs

c.1483_1484fs

1 paper

NM_021871.4

p.G498S

c.1492G>A

1 paper

NM_021871.4

p.E493K

c.1477G>A

1 paper

NM_021871.4

p.T499T

c.1497A>C

1 paper

NM_021871.4

p.P492S

c.1474C>T

1 paper

NM_021871.4

p.C491F

c.1472G>T

1 paper

NM_021871.4

p.D490E

c.1470C>G

1 paper

NM_021871.4

p.I503V

c.1507A>G

1 paper

NM_021871.4

p.G488D

c.1463G>A