Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.T424A

c.1270A>G

Surrounding Variants

1 paper

NM_021871.4

p.E427E

c.1281G>A

1 paper

NM_021871.4

p.N419D

c.1255A>G

1 paper

NM_021871.4

p.H429Q

c.1287C>G

1 paper

NM_021871.4

p.S417T

c.1249T>A

1 paper

NM_021871.4

p.V416M

c.1246G>A

1 paper

NM_021871.4

p.K432I

c.1295A>T

2 papers

NM_021871.4

p.E415*

c.1243G>T

1 paper

NM_021871.4

p.V434I

c.1300G>A

1 paper

NM_021871.4

p.E414K

c.1240G>A

1 paper

NM_021871.4

p.T435N

c.1304C>A

1 paper

NM_021871.4

p.T412S

c.1234A>T

2 papers

NM_021871.4

p.G411G

c.1233C>A