Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.S388T

c.1162T>A

Surrounding Variants

1 paper

NM_021871.4

p.W386C

c.1158G>T

1 paper

NM_021871.4

p.Q385R

c.1154A>G

1 paper

NM_021871.4

p.Q385P

c.1154A>C

1 paper

NM_021871.4

p.G384fs

c.1150_1151fs

1 paper

NM_021871.4

p.T383A

c.1147A>G

1 paper

NM_021871.4

p.R394G

c.1180A>G

1 paper

NM_021871.4

p.R394R

c.1180A>C

2 papers

NM_021871.4

p.G371_G381insFs

c.1112_1143dup32

2 papers

NM_021871.4

p.G381D

c.1142G>A

1 paper

NM_021871.4

p.G381C

c.1141G>T

2 papers

NM_021871.4

p.P395P

c.1185A>G

2 papers

NM_021871.4

p.D396N

c.1186G>A