Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.E376G

c.1127A>G

Surrounding Variants

1 paper

NM_021871.4

p.E376*

c.1126G>T

1 paper

NM_021871.4

p.S378T

c.1132T>A

1 paper

NM_021871.4

p.W373*

c.1119G>A

1 paper

NM_021871.4

p.W373*

c.1118G>A

1 paper

NM_021871.4

p.H372N

c.1114C>A

1 paper

NM_021871.4

p.G381C

c.1141G>T

2 papers

NM_021871.4

p.G381D

c.1142G>A

1 paper

NM_021871.4

p.G371E

c.1112G>A

2 papers

NM_021871.4

p.G371_G381insFs

c.1112_1143dup32

1 paper

NM_021871.4

p.T383A

c.1147A>G

1 paper

NM_021871.4

p.S369G

c.1105A>G

2 papers

NM_021871.4

p.G368delFs

c.1103delC