Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_021871.4

p.G368delFs

c.1103delC

Surrounding Variants

1 paper

NM_021871.4

p.S369G

c.1105A>G

1 paper

NM_021871.4

p.R367R

c.1101C>T

1 paper

NM_021871.4

p.R367P

c.1100G>C

1 paper

NM_021871.4

p.R367C

c.1099C>T

1 paper

NM_021871.4

p.R367S

c.1099C>A

1 paper

NM_021871.4

p.G371E

c.1112G>A

1 paper

NM_021871.4

p.H372N

c.1114C>A

1 paper

NM_021871.4

p.W373*

c.1118G>A

1 paper

NM_021871.4

p.W373*

c.1119G>A

1 paper

NM_021871.4

p.G363S

c.1087G>A

1 paper

NM_021871.4

p.W360_P362delFs

c.1078_1084del7

1 paper

NM_021871.4

p.N361K

c.1083T>G