Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.R353K

c.1058G>A

Surrounding Variants

3 papers

NM_021871.4

p.P352delFs

c.1055delG

1 paper

NM_021871.4

p.P354L

c.1061C>T

1 paper

NM_021871.4

p.P352H

c.1055C>A

1 paper

NM_021871.4

p.G355S

c.1063G>A

1 paper

NM_021871.4

p.G350V

c.1049G>T

1 paper

NM_021871.4

p.G350E

c.1049G>A

1 paper

NM_021871.4

p.S356R

c.1068T>A

1 paper

NM_021871.4

p.P349S

c.1045C>T

1 paper

NM_021871.4

p.G358*

c.1072G>T

1 paper

NM_021871.4

p.G358R

c.1072G>A

1 paper

NM_021871.4

p.G358E

c.1073G>A

1 paper

NM_021871.4

p.G358G

c.1074A>G