Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_021871.4

p.W334*

c.1002G>A

Surrounding Variants

2 papers

NM_021871.4

p.W334C

c.1002G>T

2 papers

NM_021871.4

p.W334C

c.1002G>C

10 papers

NM_021871.4

p.W334*

c.1001G>A

2 papers

NM_021871.4

p.N335Y

c.1003A>T

1 paper

NM_021871.4

p.S333N

c.998G>A

1 paper

NM_021871.4

p.G337W

c.1009G>T

1 paper

NM_021871.4

p.G337E

c.1010G>A

1 paper

NM_021871.4

p.G337G

c.1011G>T

1 paper

NM_021871.4

p.T331I

c.992C>T

1 paper

NM_021871.4

p.S338C

c.1012A>T

26 papers

NM_021871.4

p.T331A

c.991A>G

1 paper

NM_021871.4

p.S339F

c.1016C>T