Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.T318I

c.953C>T

Surrounding Variants

1 paper

NM_021871.4

p.G317G

c.951G>A

1 paper

NM_021871.4

p.G317R

c.949G>A

8 papers

NM_021871.4

p.G316*

c.946G>T

8 papers

NM_021871.4

p.T315delFs

c.945delA

2 papers

NM_021871.4

p.G316fs

c.946_947fs

1 paper

NM_021871.4

p.T315fs

c.943_944fs

1 paper

NM_021871.4

p.T315I

c.944C>T

2 papers

NM_021871.4

p.K322*

c.964A>T

1 paper

NM_021871.4

p.G314R

c.940G>A

1 paper

NM_021871.4

p.P323S

c.967C>T

1 paper

NM_021871.4

p.P323_G324ins10

c.967_971ins30

1 paper

NM_021871.4

p.R308_P323insFs

c.923_968dup46