Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.P310L

c.929C>T

Surrounding Variants

1 paper

NM_021871.4

p.S312G

c.934A>G

1 paper

NM_021871.4

p.S312insFs

c.934_935insA

5 papers

NM_021871.4

p.S312delFs

c.934delT

1 paper

NM_021871.4

p.N307Y

c.919A>T

1 paper

NM_021871.4

p.G314R

c.940G>A

1 paper

NM_021871.4

p.T315I

c.944C>T

1 paper

NM_021871.4

p.T315fs

c.943_944fs

3 papers

NM_021871.4

p.T305A

c.913A>G

1 paper

NM_021871.4

p.T305P

c.913A>C

1 paper

NM_021871.4

p.S304_T305insFs

c.912_913insA

8 papers

NM_021871.4

p.G316*

c.946G>T

8 papers

NM_021871.4

p.T315delFs

c.945delA