Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_021871.4

p.P302A

c.904C>G

Surrounding Variants

1 paper

NM_021871.4

p.P302P

c.906T>G

1 paper

NM_021871.4

p.G301A

c.902G>C

2 papers

NM_021871.4

p.G301E

c.902G>A

1 paper

NM_021871.4

p.S304G

c.910A>G

1 paper

NM_021871.4

p.S304_T305insFs

c.912_913insA

3 papers

NM_021871.4

p.T305A

c.913A>G

1 paper

NM_021871.4

p.S299G

c.895A>G

1 paper

NM_021871.4

p.T305P

c.913A>C

1 paper

NM_021871.4

p.G298G

c.894G>T

1 paper

NM_021871.4

p.G298E

c.893G>A

1 paper

NM_021871.4

p.N307Y

c.919A>T

5 papers

NM_021871.4

p.W295*

c.885G>A