Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_021871.4

p.S294G

c.880A>G

Surrounding Variants

1 paper

NM_021871.4

p.S294C

c.880A>T

1 paper

NM_021871.4

p.S294T

c.881G>C

1 paper

NM_021871.4

p.G293E

c.878G>A

2 papers

NM_021871.4

p.G293R

c.877G>A

4 papers

NM_021871.4

p.W295*

c.884G>A

5 papers

NM_021871.4

p.W295*

c.885G>A

1 paper

NM_021871.4

p.A292S

c.874G>T

1 paper

NM_021871.4

p.S291T

c.872G>C

1 paper

NM_021871.4

p.P289P

c.867T>G

1 paper

NM_021871.4

p.G298E

c.893G>A

1 paper

NM_021871.4

p.G298G

c.894G>T

1 paper

NM_021871.4

p.S299G

c.895A>G