Varaico: Literature-Extracted Genetic Variants

FGA

277 papers

RefSeq Summary

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by t...

Pfam Domains

Fib_alphaaa 49–191UCSCFibrinogen alpha/beta chain family

Fibrinogen_aCaa 445–509UCSCFibrinogen alpha C domain

Fibrinogen_Caa 628–863UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen alpha chain

HGNC Previous Name

fibrinogen, A alpha polypeptide

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021871.4

p.R287insFs

c.859_860insC

Surrounding Variants

3 papers

NM_021871.4

p.R287W

c.859A>T

1 paper

NM_021871.4

p.R287K

c.860G>A

1 paper

NM_021871.4

p.R287S

c.861G>T

1 paper

NM_021871.4

p.N288S

c.863A>G

4 papers

NM_021871.4

p.S285N

c.854G>A

1 paper

NM_021871.4

p.P289P

c.867T>G

1 paper

NM_021871.4

p.E284G

c.851A>G

1 paper

NM_021871.4

p.E284K

c.850G>A

1 paper

NM_021871.4

p.T283R

c.848C>G

1 paper

NM_021871.4

p.E282delFs

c.846delC

1 paper

NM_021871.4

p.S291T

c.872G>C

1 paper

NM_021871.4

p.E282D

c.846G>C